UEFA Champions League Betting 21/22: Matchday 05 Lines For Wednesday

Written By Alex Blowers on November 22, 2021

The UEFA Champions League returns this week for the penultimate round of the Group Stage. We have 16 fixtures spread across two days, and this article will focus on Wednesday’s fixtures. If you’re unsure about what markets to pick for these games, you can read on to see my picks and check out our UEFA Champions League Betting Guide.

Matchday 05 brings us another edition of the ‘Petrodollar Cup. ‘ Manchester City host PSG at The Etihad in what could be Sergio Ramos’ debut for the Parisians. In Group C, Sporting Lisbon and Borussia Dortmund are locked on six points and have it all to play for in their game at the José Alvalade.

Porto have a great chance of collecting three points at Anfield with Liverpool already qualified. Carlo Ancelotti takes Real Madrid on their first trip to Moldova to face FC Sheriff Tiraspol. Can this season’s favorite underdog achieve the impossible again and beat Los Blancos?

Click here to get all the info on Tuesday’s eight UEFA Champions League fixtures.

You can always hit me up on Twitter @AlexJBlowers for advice, your picks, and thoughts on what’s happening in the world of soccer.


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UEFA Champions League Betting: Matchday 05 Lines For Wednesday


  • I think Porto’s Moneyline at +275 is excellent value, and they’re available at -110 in the Double Chance market to Win or Draw. Liverpool have already won Group B, and Jürgen Klopp will likely rest all of his key players. If you want to play it safe, wait an hour till kick-off when the lineups are released. Don’t be surprised if Sportsbooks react to the news as well and shift the lines.
  • I’ve been burnt by RB Leipzig a couple of times this season, but I’m still jumping on their Moneyline at +110. They have so much attacking talent, and with nothing to lose, I’m hoping Jesse Marsch goes all out in this game. I would love to see him select Christopher Nkunku, Dani Olmo, and Dominik Szoboszlai to play behind André Silva.
  • I’m confident Real Madrid will take FC Sheriff Tiraspol a lot more seriously this time around and get the three points. At -400, there isn’t much value backing them, so combine them with Inter Milan in a Moneyline Parlay at -149.


In the US, you can legally bet on soccer in more than two dozen states. You can bet online in some states, but only in-person betting is allowed in most of them.

DraftKings Sportsbook is available in Colorado, Illinois, Indiana, Iowa, Michigan, New Hampshire, New Jersey, Pennsylvania, Tennessee, Virginia, and West Virginia.

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Betting advice for the Premier League, Bundesliga & UEFA Champions League! Twitter - @AlexJBlowers

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